JMPR-related information

ADI/PTDI: 0–0.08 mg/kg bw
Residue definition:For compliance with the MRL for plant commodities: Afidopyropen. For dietary risk assessment for plant commodities: Sum of afidopyropen + dimer of [(3R,6R,6aR,12S,12bR)-3-[(cyclopropanecarbonyl)oxy]-6,12-dihydroxy-4,6a,12b-trimethyl- 11-oxo-9-(pyridin-3-yl)-1,3,4,4a,5,6,6a,12,12a,12b-decahydro-2H,11H-naphtho[2,1-b]pyrano[3,4- e]pyran-4-yl]methyl rac-cyclopropanecarboxylate (M007). For compliance with the MRL for animal commodities: Afidopyropen For dietary risk assessment for animal commodities, excluding liver: Afidopyropen + (3S,4R,4aR,6S, 6aS, 12R,12aS,12bS)-3,6,12-trihydroxy-4-(hydroxymethyl)-4,6a, 12b- trimethyl--9-(pyridin-3-yl)-1, 3,4,4a,5,6,6a,12, 12a,12b-decahydro-2H,11H-benzo- [ƒ] pyrano[4,3- b]chromen-11-one (M001) + Cyclopropane carboxylic acid (CPCA/M061) and (2R)-3-carboxy-2- [(cyclopropyIcarbonyI)oxy]- N, N, N-trimethylpropan-1- aminium chloride (CPCA-carnitine conjugate/M060), expressed as afidopyropen. For dietary risk assessment for animal commodities, liver: Afidopyropen + (3S,4R,4aR,6S, 6aS, 12R,12aS,12bS)-3,6,12-trihydroxy-4-(hydroxymethyl)-4,6a, 12b-trimethyl--9- (pyridin-3-yl)-1, 3,4,4a,5,6,6a,12, 12a,12b-decahydro-2H,11H-benzo- [ƒ] pyrano[4,3-b]chromen-11- one (M001) + Cyclopropane carboxylic acid (CPCA/M061) and (2R)-3-carboxy-2- [(cyclopropyIcarbonyI)oxy]- N, N, N-trimethylpropan-1- aminium chloride (CPCA-carnitine conjugate/M060) + [(3S,4R,4aR,6S,6aS,12R,12aS,12bS)-3-(cyclopropylcarbonyl)oxy]-6,12-dihydroxy- 4,6a,12b-trimethyl-9-(1-oxidopyridin-3-yl)-11-oxo-1,3,4,4a,5,6,6a,12,12a,12b-decahydro-2H, 11H- benzo[f]pyrano[4,3-b]chromen-4-yl]methyl cyclopropane-carboxylate (M017), expressed as afidopyropen. The residue is not fat-soluble.